## Network Analysis Tools

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Path finding and pathway extraction

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This program was developed by Sylvain Brohée, Gilles Vanderstocken and Jacques van Helden.

In this demonstration, we will compare the networks resulting from the two first publications reporting a complete characterization of the yeast interactome, obtained using the two-hybrid method.The first network (Uetz et al, 2000) contains 865 interactions between 926 proteins.The second network (Ito et al, 2001) contains 786 interactions between 779 proteins.We will merge the two networks (i.e. compute their union), and label each edge according to the fact that it is found only in Ito's network, only in Uetz' network, or in both. We will also compute the statistical significance of the intersection between the two networks.