In this demo, the network has been already pre-loaded. We use the weighted STRING database network, a network of protein-protein interactions, as demo network. Its weights, which describe edge reliability, have been inverted to describe
edge costs. The demo network is part of our sample data collection. We want to recover a signal
transduction pathway known to regulate cell wall integrity in S. cerevisiae (Saito and Tatebayashi, J. Biochem, 2004). This pathway is reported to start with WSC1 or MID2 and to end with RLM1, SWI4 or SWI6.
We will look for the lightest paths connecting MID2 to RLM1/SWI4/SWI6, WSC1 being absent in the demo network. The paths of first rank miss one step (ROM2) and replace MPK1 by KSS1, otherwise they are correct.
ROM2 is missing in the demo network. With improved quality of the protein-protein interaction network used, path finding accuracy is expected to increase.